Combining PDE5 inhibitors like Viagra or Cialis with nitrates can cause a life-threatening drop in blood pressure. Learn why this interaction is dangerous, how long to wait between doses, and what to do if you accidentally mix them.
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Learn how to track and use professional society medication safety updates from ISMP, FDA, ASHP, and WHO to prevent errors and protect patients. Get practical steps for busy clinicians.
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Healthcare providers play a critical role in helping patients understand and accept generic medications. By explaining safety, cost savings, and addressing concerns about appearance, providers improve adherence and outcomes-turning affordability into actual care.
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First-generation antihistamines like Benadryl cause severe drowsiness and anticholinergic side effects that can last over 18 hours. Learn why they're risky for daily use, especially for older adults, and what safer alternatives exist.
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Antiplatelet medications save lives but raise the risk of stomach bleeding. Learn how to protect your GI tract with PPIs, which drugs are riskiest, when to stop them, and what to do if you bleed.
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ACE inhibitors and ARBs are strictly unsafe during pregnancy and can cause severe fetal harm. Learn the risks, the safest alternatives like labetalol and methyldopa, and what to do if you're already pregnant or planning to conceive.
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Rifampin can make birth control pills, patches, and rings ineffective by speeding up hormone breakdown. Learn why only rifampin-not other antibiotics-poses this risk, how long the danger lasts, and what backup methods actually work.
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A Drug Safety Communication from the FDA is an official alert about new risks tied to approved medications. These messages help doctors and patients make safer treatment decisions based on real-world data.
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Learn how adverse event rates are calculated in clinical trials using percentages and relative risk, why traditional methods mislead, and why the FDA now requires exposure-adjusted metrics like EAIR for accurate safety assessment.
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Generic drug shortages aren't caused by too few manufacturers-they're caused by too little profit. When competition drives prices to zero, makers walk away, leaving patients without life-saving meds.
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Dependence on foreign manufacturing for drugs has led to widespread shortages. With 90% of active ingredients coming from China and India, even small disruptions can cut off life-saving medications. Here’s how the system works-and how to fix it.
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Learn how to safely store high-risk medications like opioids and benzodiazepines using a lockbox to prevent accidental poisoning, misuse, and theft. Step-by-step guide for families with children or elderly members.
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